α-Carotene does not occupy the galectin-3 carbohydrate-recognition site in a blind docking screen benchmarked against olitigaltin
Int J Adv Interdis Res 2026, 6(2): e006 · DOI: registration in progress
Abstract
Galectin-3 is a β-galactoside-binding lectin implicated in inflammation, fibrosis and adverse ventricular remodelling after myocardial infarction, and dietary phytochemicals are frequently screened against it by molecular docking. Such screens rarely include a reference inhibitor, and rarely verify where the predicted ligand actually binds. We docked eight …
